Current Perspectives: focused commentary: Key cells in asthma

Por Umetsu, Dale T, DeKruyff, Rosemarie H.
Publicado em 2010

The many paths to asthma: phenotype shaped by innate and adaptive immunity

Por Kim, Hye Young, DeKruyff, Rosemarie H, Umetsu, Dale T
Publicado em 2010

Allergen-specific Th1 cells fail to counterbalance Th2 cell–induced airway hyperreactivity but cause severe airway inflammation

Por Hansen, Gesine, Berry, Gerald, DeKruyff, Rosemarie H., Umetsu, Dale T.
Publicado em 1999

TIM genes: a family of cell surface phosphatidylserine receptors that regulate innate and adaptive immunity

Por Freeman, Gordon J., Casasnovas, Jose M., Umetsu, Dale T., DeKruyff, Rosemarie H.
Publicado em 2010

Direct activation of natural killer T cells induces airway hyperreactivity in nonhuman primates

Por Matangkasombut, Ponpan, Pichavant, Muriel, Yasumi, Takahiro, Hendricks, Carrie, Savage, Paul B., DeKruyff, Rosemarie H., Umetsu, Dale T.
Publicado em 2008

Tim-1 stimulation of dendritic cells regulates the balance between effector and regulatory T cells

Por Xiao, Sheng, Zhu, Bing, Jin, Hulin, Zhu, Chen, Umetsu, Dale T., DeKruyff, Rosemarie H., Kuchroo, Vijay K.
Publicado em 2011

Tim-1-Mediated T Cell Activation Requires Recruitment and Activation of PI 3-Kinase

Por de Souza, Anjali J., Oak, Jean S., Jordanhazy, Ryan, DeKruyff, Rosemarie H., Fruman, David A., Kane, Lawrence P.
Publicado em 2008

TIM-1 and TIM-3 enhancement of Th2 cytokine production by mast cells

Por Nakae, Susumu, Iikura, Motoyasu, Suto, Hajime, Akiba, Hisaya, Umetsu, Dale T., DeKruyff, Rosemarie H., Saito, Hirohisa, Galli, Stephen J.
Publicado em 2007

ICOS/ICOSL Interaction Is Required for CD4(+) Invariant NKT Cell Function and Homeostatic Survival

Por Akbari, Omid, Stock, Philippe, Meyer, Everett H., Freeman, Gordon J., Sharpe, Arlene H., Umetsu, Dale T., DeKruyff, Rosemarie H.
Publicado em 2008

Distinct trafficking of cell surface and endosomal TIM-1 to the immune synapse

Por Echbarthi, Meriem, Zonca, Manuela, Mellwig, Rachel, Schwab, Yannick, Kaplan, Gerardo, DeKruyff, Rosemarie H., Roda-Navarro, Pedro, Casasnovas, Jose M.
Publicado no Traffic (2015)

Immunoglobulin A (IgA) Is a Natural Ligand of Hepatitis A Virus Cellular Receptor 1 (HAVCR1), and the Association of IgA with HAVCR1 Enhances Virus-Receptor Interactions

Por Tami, Cecilia, Silberstein, Erica, Manangeeswaran, Mohanraj, Freeman, Gordon J., Umetsu, Sarah E., DeKruyff, Rosemarie H., Umetsu, Dale T., Kaplan, Gerardo G.
Publicado em 2007

Novel Genetic Regulation of  T Helper 1 (Th1)/Th2 Cytokine Production and Encephalitogenicity in Inbred Mouse Strains

Por Conboy, Irina M., DeKruyff, Rosemarie H., Tate, Keri M., Cao, Zhu A., Moore, Tom A., Umetsu, Dale T., Jones, Patricia P.
Publicado em 1997

Lymphoid Organ-Resident Dendritic Cells Exhibit Unique Transcriptional Fingerprints Based on Subset and Site

Por Elpek, Kutlu G., Bellemare-Pelletier, Angelique, Malhotra, Deepali, Reynoso, Erika D., Lukacs-Kornek, Veronika, DeKruyff, Rosemarie H., Turley, Shannon J.
Publicado em 2011

CD4(+) T helper cells engineered to produce latent TGF-β1 reverse allergen-induced airway hyperreactivity and inflammation

Por Hansen, Gesine, McIntire, Jennifer J., Yeung, V. Peter, Berry, Gerald, Thorbecke, G. Jeanette, Chen, Lizhen, DeKruyff, Rosemarie H., Umetsu, Dale T.
Publicado em 2000

Tim-1 Signaling Substitutes for Conventional Signal 1 and Requires Costimulation to Induce T Cell Proliferation()

Por Mariat, Christophe, Degauque, Nicolas, Balasubramanian, Savithri, Kenny, James, DeKruyff, Rosemarie H., Umetsu, Dale T., Kuchroo, Vijay, Zheng, Xin Xiao, Strom, Terry B.
Publicado em 2009

Glycolipid activation of invariant T cell receptor(+) NK T cells is sufficient to induce airway hyperreactivity independent of conventional CD4(+) T cells

Por Meyer, Everett H., Goya, Sho, Akbari, Omid, Berry, Gerald J., Savage, Paul B., Kronenberg, Mitchell, Nakayama, Toshinori, DeKruyff, Rosemarie H., Umetsu, Dale T.
Publicado em 2006

TIM-4, expressed by medullary macrophages, regulates respiratory tolerance by mediating phagocytosis of antigen-specific T cells

Por Albacker, Lee A, Yu, Sanhong, Bedoret, Denis, Lee, Wan-Ling, Umetsu, Sarah E, Monahan, Sheena, Freeman, Gordon J, Umetsu, Dale T, DeKruyff, Rosemarie H
Publicado no Mucosal Immunol (2012)

Activation of Nonclassical CD1d-Restricted NK T Cells Induces Airway Hyperreactivity in β(2)-Microglobulin-Deficient Mice()

Por Koh, Youngil I., Kim, Hye Young, Meyer, Everett H., Pichavant, Muriel, Akbari, Omid, Yasumi, Takahiro, Savage, Paul B., DeKruyff, Rosemarie H., Umetsu, Dale T.
Publicado no J Immunol (2008)

Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity

Por Chang, Ya-Jen, Kim, Hye Young, Albacker, Lee A, Baumgarth, Nicole, McKenzie, Andrew N J, Smith, Dirk E, DeKruyff, Rosemarie H, Umetsu, Dale T
Publicado em 2011

A Fungal Glycosphingolipid Directly Activates Natural Killer T Cells and Rapidly Induces Airways Disease

Por Albacker, Lee A., Chaudhary, Vinod, Chang, Ya-Jen, Kim, Hye Young, Chuang, Ya-Ting, Pichavant, Muriel, DeKruyff, Rosemarie H., Savage, Paul B., Umetsu, Dale T.
Publicado em 2013