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Activation of Nonclassical CD1d-Restricted NK T Cells Induces Airway Hyperreactivity in β(2)-Microglobulin-Deficient Mice()

Allergic asthma is characterized by Th2-driven eosinophilic airway inflammation and by a central feature called airway hyperreactivity (AHR), development of which requires the presence of classical type I invariant NK T (iNKT) cells. Allergen-induced AHR, however, develops in β(2)-microglobulin (β(2...

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Publicat a:J Immunol
Autors principals: Koh, Youngil I., Kim, Hye Young, Meyer, Everett H., Pichavant, Muriel, Akbari, Omid, Yasumi, Takahiro, Savage, Paul B., DeKruyff, Rosemarie H., Umetsu, Dale T.
Format: Artigo
Idioma:Inglês
Publicat: 2008
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4884641/
https://ncbi.nlm.nih.gov/pubmed/18802058
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