iNKT Cells Require CCR4 to Localize to the Airways and to Induce Airway Hyperreactivity

iNKT cells are required for the induction of airway hyperreactivity (AHR), a cardinal feature of asthma, but how iNKT cells traffic to the lungs to induce AHR has not been previously studied. Using several models of asthma, we demonstrated that iNKT cells required the chemokine receptor CCR4 for pul...

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Detalhes bibliográficos
Main Authors: Meyer, Everett H., Wurbel, Marc-André, Staton, Tracy L., Pichavant, Muriel, Kan, Matthew J., Savage, Paul B., DeKruyff, Rosemarie H., Butcher, Eugene C., Campbell, James J., Umetsu, Dale T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2564604/
https://ncbi.nlm.nih.gov/pubmed/17878364
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