Apoptotic Cells Activate NKT Cells through T Cell Ig-Like Mucin-Like–1 Resulting in Airway Hyperreactivity

T cell Ig-like mucin-like–1 (TIM-1) is an important asthma susceptibility gene, but the immunological mechanisms by which TIM-1 functions remain uncertain. TIM-1 is also a receptor for phosphatidylserine (PtdSer), an important marker of cells undergoing programmed cell death, or apoptosis. We now de...

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Bibliografiske detaljer
Main Authors: Lee, Hyun-Hee, Meyer, Everett H., Goya, Sho, Pichavant, Muriel, Kim, Hye Young, Bu, Xia, Umetsu, Sarah E., Jones, Jennifer C., Savage, Paul B., Iwakura, Yoichiro, Casasnovas, Jose M., Kaplan, Gerardo, Freeman, Gordon J., DeKruyff, Rosemarie H., Umetsu, Dale T.
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3114419/
https://ncbi.nlm.nih.gov/pubmed/20889552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1001116
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