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Allergen-specific Th1 cells fail to counterbalance Th2 cell–induced airway hyperreactivity but cause severe airway inflammation

Allergic asthma, which is present in as many as 10% of individuals in industrialized nations, is characterized by chronic airway inflammation and hyperreactivity induced by allergen-specific Th2 cells secreting interleukin-4 (IL-4) and IL-5. Because Th1 cells antagonize Th2 cell functions, it has be...

詳細記述

保存先:
書誌詳細
出版年:J Clin Invest
主要な著者: Hansen, Gesine, Berry, Gerald, DeKruyff, Rosemarie H., Umetsu, Dale T.
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Clinical Investigation 1999
主題:
オンライン・アクセス:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC407883/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9916129/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI5155
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