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Innate lymphoid cells mediate influenza-induced airway hyper-reactivity independently of adaptive immunity

Patients with asthma, a major public health problem, are at high risk for serious disease from influenza virus infection, but the pathogenic mechanisms by which influenza A causes airway disease and asthma are not fully known. We show here in a mouse model that influenza infection acutely induced ai...

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Detalhes bibliográficos
Main Authors: Chang, Ya-Jen, Kim, Hye Young, Albacker, Lee A, Baumgarth, Nicole, McKenzie, Andrew N J, Smith, Dirk E, DeKruyff, Rosemarie H, Umetsu, Dale T
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3417123/
https://ncbi.nlm.nih.gov/pubmed/21623379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2045
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