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Tim-1 stimulation of dendritic cells regulates the balance between effector and regulatory T cells
We show that Tim-1, initially reported to be expressed on CD4(+) T cells, is constitutively expressed on dendritic cells (DC) and that its expression further increases after DC maturation. Tim-1 signaling into DC upregulates costimulatory molecule expression and proinflammatory cytokine production,...
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| 主要な著者: | , , , , , , |
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| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2011
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3129006/ https://ncbi.nlm.nih.gov/pubmed/21469101 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201040993 |
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