Functional Characterization of Mammalian Inositol 1,4,5-Trisphosphate Receptor Isoforms

Por Tu, Huiping, Wang, Zhengnan, Nosyreva, Elena, De Smedt, Humbert, Bezprozvanny, Ilya
Publicado em 2005

Endoplasmic-Reticulum Calcium Depletion and Disease

Por Mekahli, Djalila, Bultynck, Geert, Parys, Jan B., De Smedt, Humbert, Missiaen, Ludwig
Publicado em 2011

Regulation of inositol 1,4,5-trisphosphate-induced Ca(2+) release by reversible phosphorylation and dephosphorylation

Por VANDERHEYDEN, Veerle, DEVOGELAERE, Benoit, MISSIAEN, Ludwig, DE SMEDT, Humbert, BULTYNCK, Geert, PARYS, Jan B.
Publicado em 2008

Reciprocal sensitivity of diffuse large B-cell lymphoma cells to Bcl-2 inhibitors BIRD-2 versus venetoclax

Por Vervloessem, Tamara, Akl, Haidar, Tousseyn, Thomas, De Smedt, Humbert, Parys, Jan B., Bultynck, Geert
Publicado no Oncotarget (2017)

REGULATION OF INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR TYPE 1 FUNCTION DURING OOCYTE MATURATION BY MPM-2 PHOSPHORYLATION

Por VANDERHEYDEN, Veerle, WAKAI, Takuya, BULTYNCK, Geert, DE SMEDT, Humbert, PARYS, Jan B., FISSORE, Rafael A.
Publicado em 2009

IP(3) Receptors, Mitochondria, and Ca(2+) Signaling: Implications for Aging

Por Decuypere, Jean-Paul, Monaco, Giovanni, Missiaen, Ludwig, De Smedt, Humbert, Parys, Jan B., Bultynck, Geert
Publicado em 2011

STIM1 as a key regulator for Ca(2+ )homeostasis in skeletal-muscle development and function

Por Kiviluoto, Santeri, Decuypere, Jean-Paul, De Smedt, Humbert, Missiaen, Ludwig, Parys, Jan B, Bultynck, Geert
Publicado em 2011

Unraveling the role of polycystin-2/inositol 1,4,5-trisphosphate receptor interaction in Ca(2+) signaling

Por Sammels, Eva, Devogelaere, Benoit, Mekahli, Djalila, Bultynck, Geert, Missiaen, Ludwig, Parys, Jan B, De Smedt, Humbert
Publicado em 2010

Localization and function of a calmodulin-apocalmodulin-binding domain in the N-terminal part of the type 1 inositol 1,4,5-trisphosphate receptor.

Por Sienaert, Ilse, Nadif Kasri, Nael, Vanlingen, Sara, Parys, Jan B, Callewaert, Geert, Missiaen, Ludwig, de Smedt, Humbert
Publicado em 2002

The three isoenzymes of human inositol-1,4,5-trisphosphate 3-kinase show specific intracellular localization but comparable Ca2+ responses on transfection in COS-7 cells.

Por Dewaste, Valérie, Moreau, Colette, De Smedt, Florence, Bex, Françoise, De Smedt, Humbert, Wuytack, Frank, Missiaen, Ludwig, Erneux, Christophe
Publicado em 2003

Thimerosal stimulates Ca(2+) flux through inositol 1,4,5-trisphosphate receptor type 1, but not type 3, via modulation of an isoform-specific Ca(2+)-dependent intramolecular intera...

Por Bultynck, Geert, Szlufcik, Karolina, Kasri, Nael Nadif, Assefa, Zerihun, Callewaert, Geert, Missiaen, Ludwig, Parys, Jan B., De Smedt, Humbert
Publicado em 2004

mTOR-Controlled Autophagy Requires Intracellular Ca(2+) Signaling

Por Decuypere, Jean-Paul, Kindt, Dimphny, Luyten, Tomas, Welkenhuyzen, Kirsten, Missiaen, Ludwig, De Smedt, Humbert, Bultynck, Geert, Parys, Jan B.
Publicado em 2013

Polycystin-2 Activation by Inositol 1,4,5-Trisphosphate-induced Ca(2+) Release Requires Its Direct Association with the Inositol 1,4,5-Trisphosphate Receptor in a Signaling Microdo...

Por Sammels, Eva, Devogelaere, Benoit, Mekahli, Djalila, Bultynck, Geert, Missiaen, Ludwig, Parys, Jan B., Cai, Yiqiang, Somlo, Stefan, De Smedt, Humbert
Publicado em 2010

Phosphorylation of IP(3)R1 and the regulation of [Ca(2+)](i) responses at fertilization: a role for the MAP kinase pathway

Por Lee, Bora, Vermassen, Elke, Yoon, Sook-Young, Vanderheyden, Veerle, Ito, Junya, Alfandari, Dominique, De Smedt, Humbert, Parys, Jan B., Fissore, Rafael A.
Publicado em 2006

HA14-1, but not the BH3 mimetic ABT-737, causes Ca(2+) dysregulation in platelets and human cell lines

Por Akl, Haidar, Vandecaetsbeek, Ilse, Monaco, Giovanni, Kauskot, Alexandre, Luyten, Tomas, Welkenhuyzen, Kirsten, Hoylaerts, Marc, De Smedt, Humbert, Parys, Jan B., Bultynck, Geert
Publicado em 2013

Protein phosphatase-1 is a novel regulator of the interaction between IRBIT and the inositol 1,4,5-trisphosphate receptor

Por Devogelaere, Benoit, Beullens, Monique, Sammels, Eva, Derua, Rita, Waelkens, Etienne, vanLint, Johan, Parys, Jan B., Missiaen, Ludwig, Bollen, Mathieu, DeSmedt, Humbert
Publicado em 2007

Effects of the immunosuppressant FK506 on intracellular Ca(2+) release and Ca(2+) accumulation mechanisms

Por Bultynck, Geert, De Smet, Patrick, Weidema, A Frederik, Ver Heyen, Mark, Maes, Karlien, Callewaert, Geert, Missiaen, Ludwig, Parys, Jan B, De Smedt, Humbert
Publicado em 2000

Everolimus halts hepatic cystogenesis in a rodent model of polycystic-liver-disease

Por Temmerman, Frederik, Chen, Feng, Libbrecht, Louis, Vander Elst, Ingrid, Windmolders, Petra, Feng, Yuanbo, Ni, Yicheng, De Smedt, Humbert, Nevens, Frederik, van Pelt, Jos
Publicado no World J Gastroenterol (2017)

INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR 1, A WIDESPREAD Ca(2+)CHANNEL, IS A NOVEL SUBSTRATE OF POLO-LIKE KINASE 1 IN EGGS

Por Ito, Junya, Yoon, Sook-Young, Lee, Bora, Vanderheyden, Veerle, Vermassen, Elke, Wojcikiewicz, Richard, Alfandari, Dominique, De Smedt, Humbert, Parys, Jan B., Fissore, Rafael A.
Publicado em 2008

Caspase-3-truncated type 1 inositol 1,4,5-trisphosphate receptor enhances intracellular Ca(2+) leak and disturbs Ca(2+) signalling

Por Verbert, Leen, Lee, Bora, Kocks, Sarah L., Assefa, Zerihun, Parys, Jan B., Missiaen, Ludwig, Callewaert, Geert, Fissore, Rafael A., De Smedt, Humbert, Bultynck, Geert
Publicado em 2008