INOSITOL 1,4,5-TRISPHOSPHATE RECEPTOR 1, A WIDESPREAD Ca(2+)CHANNEL, IS A NOVEL SUBSTRATE OF POLO-LIKE KINASE 1 IN EGGS

To initiate embryo development, the sperm induces in the egg release of intracellular calcium ([Ca(2+)](i)). During oocyte maturation, the inositol-1,4,5-trisphosphate receptor (IP(3)R1), the channel implicated, undergoes modifications that enhance its function. We found that IP(3)R1 becomes phospho...

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Detalhes bibliográficos
Main Authors: Ito, Junya, Yoon, Sook-Young, Lee, Bora, Vanderheyden, Veerle, Vermassen, Elke, Wojcikiewicz, Richard, Alfandari, Dominique, De Smedt, Humbert, Parys, Jan B., Fissore, Rafael A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2895400/
https://ncbi.nlm.nih.gov/pubmed/18621368
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ydbio.2008.05.548
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