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Unraveling the role of polycystin-2/inositol 1,4,5-trisphosphate receptor interaction in Ca(2+) signaling

Autosomal dominant polycystic kidney disease (ADPKD) arises as a consequence of mutations of the genes PKD1 and PKD2, encoding respectively the integral membrane proteins polycystin-1 and polycystin-2 (TRPP2), resulting in a disturbance in intracellular Ca(2+) signaling. Previously we investigated t...

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Main Authors: Sammels, Eva, Devogelaere, Benoit, Mekahli, Djalila, Bultynck, Geert, Missiaen, Ludwig, Parys, Jan B, De Smedt, Humbert
格式: Artigo
語言:Inglês
出版: Landes Bioscience 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3038055/
https://ncbi.nlm.nih.gov/pubmed/21331231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cib.3.6.12751
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