On the Promise of Pharmacotherapies Targeted at Cognitive and Neurodegenerative Components of Down Syndrome

Por Costa, Alberto C.S.
Publicado em 2011

The Proteins of Human Chromosome 21

Por Gardiner, Katheleen, Costa, Alberto C. S.
Publicado em 2006

Exaggerated NMDA mediated LTD in a mouse model of Down syndrome and pharmacological rescuing by memantine

Por Scott-McKean, Jonah J., Costa, Alberto C.S.
Publicado em 2011

Behavioral validation of the Ts65Dn mouse model for Down syndrome of a genetic background free of the retinal degeneration mutation Pdeb(rd1)

Por Costa, Alberto C. S., Stasko, Melissa R., Schmidt, Cecilia, Davisson, Muriel T.
Publicado em 2009

Editing of the Serotonin 2C Receptor Pre-mRNA: Effects of the Morris Water Maze

Por Du, Yunzhi, Stasko, Melissa, Costa, Alberto C., Davisson, Muriel T., Gardiner, Katheleen J.
Publicado em 2007

5-HT(1A) Receptor Null Mutant Mice Responding Under a Differential-Reinforcement-of-Low-Rate 72-Second Schedule of Reinforcement

Por Scott-McKean, Jonah J., Wenger, Galen R., Tecott, Laurence H., Costa, Alberto C.S.
Publicado em 2008

Protein Profiles Associated With Context Fear Conditioning and Their Modulation by Memantine

Por Ahmed, Md. Mahiuddin, Dhanasekaran, A. Ranjitha, Block, Aaron, Tong, Suhong, Costa, Alberto C. S., Gardiner, Katheleen J.
Publicado em 2014

Generation of Integration‐Free Induced Pluripotent Stem Cells from Urine‐Derived Cells Isolated from Individuals with Down Syndrome

Por M. Lee, Young, Zampieri, Bruna L., Scott‐McKean, Jonah J., Johnson, Mark W., Costa, Alberto C.S.
Publicado no Stem Cells Transl Med (2017)

Molecular responses of the Ts65Dn and Ts1Cje mouse models of Down syndrome to MK-801

Por Siddiqui, Almas, Lacroix, Thomas, Stasko, Melissa R., Scott-McKean, Jonah J., Costa, Alberto C.S., Gardiner, Katheleen J.
Publicado em 2008

Deletion of the Glutamate Receptor 5 Subunit of Kainate Receptors Affects the Development of Morphine Tolerance

Por Bogulavsky, Johanna J., Gregus, Ann M., Kim, Paul T.-H., Costa, Alberto C. S., Rajadhyaksha, Anjali M., Inturrisi, Charles E.
Publicado em 2009

Spinal mediators that may contribute selectively to antinociceptive tolerance but not other effects of morphine as revealed by deletion of GluR5

Por Gregus, Ann M., Inra, Christopher N., Giordano, Thomas P., Costa, Alberto C.S., Rajadhyaksha, Anjali M., Inturrisi, Charles E.
Publicado em 2010

Protein Dynamics Associated with Failed and Rescued Learning in the Ts65Dn Mouse Model of Down Syndrome

Por Ahmed, Md. Mahiuddin, Dhanasekaran, A. Ranjitha, Block, Aaron, Tong, Suhong, Costa, Alberto C. S., Stasko, Melissa, Gardiner, Katheleen J.
Publicado no PLoS One (2015)

The Mouse Model of Down Syndrome Ts65Dn Presents Visual Deficits as Assessed by Pattern Visual Evoked Potentials

Por Scott-McKean, Jonah Jacob, Chang, Bo, Hurd, Ronald E., Nusinowitz, Steven, Schmidt, Cecilia, Davisson, Muriel T., Costa, Alberto C. S.
Publicado em 2010

Deletion of the GluR5 subunit of kainate receptors affects cocaine sensitivity and preference

Por Gregus, Ann M., Tropea, Thomas F., Wang, Yanran, Hauck, Stefanie C. R., Costa, Alberto C.S., Rajadhyaksha, Anjali M., Inturrisi, Charles E.
Publicado em 2009

Soluble Prion Protein and Its N-terminal Fragment Prevent Impairment of Synaptic Plasticity by Aβ Oligomers: Implications for Novel Therapeutic Strategy in Alzheimer’s Disease

Por Scott-McKean, Jonah J., Surewicz, Krystyna, Choi, Jin-Kyu, Ruffin, Vernon A., Salameh, Ahlam I., Nieznanski, Krzysztof, Costa, Alberto C.S., Surewicz, Witold K.
Publicado no Neurobiol Dis (2016)

Sustained hippocampal IL-1β overexpression impairs contextual and spatial memory in transgenic mice

Por Hein, Amy M., Stasko, Melissa R., Matousek, Sarah B., Scott-McKean, Jonah J., Maier, Steven F., Olschowka, John A., Costa, Alberto C.S., O’Banion, M. Kerry
Publicado em 2009

Human Sensory Neurons Derived from Induced Pluripotent Stem Cells Support Varicella-Zoster Virus Infection

Por Lee, Katherine S., Zhou, Wenbo, Scott-McKean, Jonah J., Emmerling, Kaitlin L., Cai, Guang-yun, Krah, David L., Costa, Alberto C., Freed, Curt R., Levin, Myron J.
Publicado em 2012

Genetic analysis of Down syndrome-associated heart defects in mice

Por Liu, Chunhong, Morishima, Masae, Yu, Tao, Matsui, Sei-Ichi, Zhang, Li, Fu, Dawei, Pao, Annie, Costa, Alberto C., Gardiner, Katheleen J., Cowell, John K., Nowak, Norma J., Parmacek, Michael S., Liang, Ping, Baldini, Antonio, Yu, Y. Eugene
Publicado em 2011