Genetic analysis of Down syndrome-associated heart defects in mice

Human trisomy 21, the chromosomal basis of Down syndrome (DS), is the most common genetic cause of heart defects. Regions on human chromosome 21 (Has21) are syntenically conserved with three regions located on mouse chromosome 10 (Mmu10), Mmu16 and Mmu17. In this study, we have analyzed the impact o...

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Detalhes bibliográficos
Main Authors: Liu, Chunhong, Morishima, Masae, Yu, Tao, Matsui, Sei-Ichi, Zhang, Li, Fu, Dawei, Pao, Annie, Costa, Alberto C., Gardiner, Katheleen J., Cowell, John K., Nowak, Norma J., Parmacek, Michael S., Liang, Ping, Baldini, Antonio, Yu, Y. Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257027/
https://ncbi.nlm.nih.gov/pubmed/21442329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00439-011-0980-2
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