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Gene-dosage effects in Down syndrome and trisomic mouse models
The abnormalities found in human Down syndrome (trisomy 21) have been thought to result from increased expression of genes on chromosome 21 because of their higher gene dosage. Now, several groups have shown this to be generally the case, but some inter-individual variability and other exceptions we...
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC545589/ https://ncbi.nlm.nih.gov/pubmed/15461808 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gb-2004-5-10-244 |
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