Non-trisomic Homeobox Gene Expression during Craniofacial Development in the Ts65Dn Mouse Model of Down Syndrome

Trisomy 21 in humans causes cognitive impairment, craniofacial dysmorphology, and heart defects collectively referred to as Down syndrome. Yet, the pathophysiology of these phenotypes is not well understood. Craniofacial alterations may lead to complications in breathing, eating, and communication....

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Autori principali: Billingsley, Cherie N., Allen, Jared R., Baumann, Douglas D., Deitz, Samantha L., Blazek, Joshua D., Newbauer, Abby, Darrah, Andrew, Long, Brad C., Young, Brandon, Clement, Mark, Doerge, R.W., Roper, Randall J.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3729611/
https://ncbi.nlm.nih.gov/pubmed/23843306
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ajmg.a.36006
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