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Perinatal Loss of Ts65Dn Down Syndrome Mice
Ts65Dn mice inherit a marker chromosome, T(17(16))65Dn, producing segmental trisomy for orthologs of about half of the genes on human chromosome 21. These mice display a number of phenotypes that are directly comparable to those in humans with trisomy 21 and are the most widely used animal model of...
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| Autores principales: | , , , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Copyright © 2006 by the Genetics Society of America
2006
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1456171/ https://ncbi.nlm.nih.gov/pubmed/16172497 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.105.050898 |
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