Molecular Characterization of the Translocation Breakpoints in the Down Syndrome Mouse Model, Ts65Dn

Ts65Dn is a mouse model of Down syndrome; a syndrome that results from Chromosome (Chr) 21 trisomy and is associated with congenital defects, cognitive impairment, and ultimately Alzheimer’s Disease. Ts65Dn mice have segmental trisomy for distal mouse Chr 16, a region sharing conserved synteny with...

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Detalhes bibliográficos
Main Authors: Reinholdt, Laura G., Ding, Yueming, Gilbert, Griffith J., Czechanski, Anne, Solzak, Jeffrey P., Roper, Randall J., Johnson, Mark T., Donahue, Leah Rae, Lutz, Cathleen, Davisson, Muriel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3505986/
https://ncbi.nlm.nih.gov/pubmed/21953412
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-011-9357-z
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