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Disruption of bone development and homeostasis by trisomy in Ts65Dn Down syndrome mice

Down syndrome (DS) is a genetic disorder resulting from trisomy 21 that causes cognitive impairment, low muscle tone and craniofacial alterations. Morphometric studies of the craniofacial and appendicular skeleton in individuals with DS suggest that bone development and homeostasis are affected by t...

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Autors principals: Blazek, Joshua D., Gaddy, Anna, Meyer, Rachel, Roper, Randall J., Li, Jiliang
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3021595/
https://ncbi.nlm.nih.gov/pubmed/20870049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2010.09.028
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