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Increased male reproductive success in Ts65Dn “Down syndrome” mice

The Ts65Dn mouse is trisomic for orthologs of about half the genes on Hsa21. A number of phenotypes in these trisomic mice parallel those in humans with trisomy 21 (Down syndrome), including cognitive deficits due to hippocampal malfunction that are sufficiently similar to human that “therapies” dev...

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Hlavní autoři: Moore, Clara S., Hawkins, Charles, Franca, Arianna, Lawler, Ann, Devenney, Benjamin, Das, Ishita, Reeves, Roger H.
Médium: Artigo
Jazyk:Inglês
Vydáno: Springer-Verlag 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002156/
https://ncbi.nlm.nih.gov/pubmed/21110029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-010-9300-8
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