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Increased male reproductive success in Ts65Dn “Down syndrome” mice

The Ts65Dn mouse is trisomic for orthologs of about half the genes on Hsa21. A number of phenotypes in these trisomic mice parallel those in humans with trisomy 21 (Down syndrome), including cognitive deficits due to hippocampal malfunction that are sufficiently similar to human that “therapies” dev...

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Detalhes bibliográficos
Main Authors: Moore, Clara S., Hawkins, Charles, Franca, Arianna, Lawler, Ann, Devenney, Benjamin, Das, Ishita, Reeves, Roger H.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer-Verlag 2010
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3002156/
https://ncbi.nlm.nih.gov/pubmed/21110029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00335-010-9300-8
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