A mouse model of Down syndrome trisomic for all human chromosome 21 syntenic regions

Down syndrome (DS) is caused by the presence of an extra copy of human chromosome 21 (Hsa21) and is the most common genetic cause for developmental cognitive disability. The regions on Hsa21 are syntenically conserved with three regions located on mouse chromosome 10 (Mmu10), Mmu16 and Mmu17. In thi...

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Detalhes bibliográficos
Main Authors: Yu, Tao, Li, Zhongyou, Jia, Zhengping, Clapcote, Steven J., Liu, Chunhong, Li, Shaomin, Asrar, Suhail, Pao, Annie, Chen, Rongqing, Fan, Ni, Carattini-Rivera, Sandra, Bechard, Allison R., Spring, Shoshana, Henkelman, R. Mark, Stoica, George, Matsui, Sei-Ichi, Nowak, Norma J., Roder, John C., Chen, Chu, Bradley, Allan, Yu, Y. Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2010
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2893810/
https://ncbi.nlm.nih.gov/pubmed/20442137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddq179
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