Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice

As the genomic basis for Down syndrome (DS), human trisomy 21 is the most common genetic cause of intellectual disability in children and young people. The genomic regions on human chromosome 21 (Hsa21) are syntenic to three regions in the mouse genome, located on mouse chromosome 10 (Mmu10), Mmu16...

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Detalhes bibliográficos
Main Authors: Yu, Tao, Liu, Chunhong, Belichenko, Pavel, Clapcote, Steven J., Li, Shaomin, Pao, Annie, Kleschevnikov, Alexander, Bechard, Allison R., Asrar, Suhail, Chen, Rongqing, Fan, Ni, Zhou, Zhenyu, Jia, Zhengping, Chen, Chu, Roder, John C., Liu, Bin, Baldini, Antonio, Mobley, William C., Yu, Y. Eugene
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3027718/
https://ncbi.nlm.nih.gov/pubmed/20932954
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2010.09.107
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