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Genetic analysis of Down syndrome facilitated by mouse chromosome engineering
Human trisomy 21 is the most frequent live-born human aneuploidy and causes a constellation of disease phenotypes classified as Down syndrome, which include heart defects, myeloproliferative disorder, cognitive disabilities and Alzheimer-type neurodegeneration. Because these phenotypes are associate...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3329253/ https://ncbi.nlm.nih.gov/pubmed/22126738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/bbug.3.1.17696 |
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