Human chromosome 21 orthologous region on mouse chromosome 17 is a major determinant of Down syndrome-related developmental cognitive deficits

Trisomy 21 (Down syndrome, DS) is the most common genetic cause of developmental cognitive deficits, and the so-called Down syndrome critical region (DSCR) has been proposed as a major determinant of this phenotype. The regions on human chromosome 21 (Hsa21) are syntenically conserved on mouse chrom...

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Autores principales: Zhang, Li, Meng, Kai, Jiang, Xiaoling, Liu, Chunhong, Pao, Annie, Belichenko, Pavel V., Kleschevnikov, Alexander M., Josselyn, Sheena, Liang, Ping, Ye, Ping, Mobley, William C., Yu, Y. Eugene
Formato: Artigo
Lenguaje:Inglês
Publicado: Oxford University Press 2014
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Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3888256/
https://ncbi.nlm.nih.gov/pubmed/24041763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddt446
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