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Behavioral validation of the Ts65Dn mouse model for Down syndrome of a genetic background free of the retinal degeneration mutation Pdeb(rd1)

The Ts65Dn mouse is the most studied and complete aneuploid model of Down syndrome (DS) widely available. As a model for human trisomy 21, these mice display many attractive features, including performance deficits in different behavioral tasks, alterations in synaptic plasticity and adult neurogene...

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Detalhes bibliográficos
Main Authors: Costa, Alberto C. S., Stasko, Melissa R., Schmidt, Cecilia, Davisson, Muriel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2783207/
https://ncbi.nlm.nih.gov/pubmed/19720087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2009.08.034
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