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On the Promise of Pharmacotherapies Targeted at Cognitive and Neurodegenerative Components of Down Syndrome
Down syndrome (DS) is the phenotypic consequence of trisomy 21 and is the most common genetically defined cause of intellectual disability. The most complete, widely available, and well-studied animal model of DS is the Ts65Dn mouse. Recent preclinical successes in rescuing learning and memory defic...
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| Autor principal: | |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
S. Karger AG
2011
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3254040/ https://ncbi.nlm.nih.gov/pubmed/21893967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000330861 |
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