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Spinal mediators that may contribute selectively to antinociceptive tolerance but not other effects of morphine as revealed by deletion of GluR5
Several groups maintain that morphine tolerance and dependence correlate with increased activity of protein kinases ERK1/2 and P38 MAPK and PKC as well as elevated levels of the neuropeptides dynorphin (DYN), substance P (sP) and calcitonin gene-related peptide (CGRP) in spinal cord dorsal horn (SCD...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2900492/ https://ncbi.nlm.nih.gov/pubmed/20359526 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuroscience.2010.03.051 |
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