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Spinal NADPH Oxidase is a Source of Superoxide in the Development of Morphine-Induced Hyperalgesia and Antinociceptive Tolerance
The role of superoxide and its active byproduct peroxynitrite as mediators of nociceptive signaling is emerging. We have recently reported that nitration and inactivation of spinal mitochondrial superoxide dismutase (MnSOD) provides a critical source of these reactive oxygen and nitrogen species dur...
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| Main Authors: | , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2010
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2933278/ https://ncbi.nlm.nih.gov/pubmed/20637262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.07.013 |
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