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Spinal NADPH Oxidase is a Source of Superoxide in the Development of Morphine-Induced Hyperalgesia and Antinociceptive Tolerance

The role of superoxide and its active byproduct peroxynitrite as mediators of nociceptive signaling is emerging. We have recently reported that nitration and inactivation of spinal mitochondrial superoxide dismutase (MnSOD) provides a critical source of these reactive oxygen and nitrogen species dur...

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Bibliografski detalji
Glavni autori: Doyle, Tim, Bryant, Leesa, Muscoli, Carolina, Cuzzocrea, Salvatore, Esposito, Emanuela, Chen, Zhoumou, Salvemini, Daniela
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2933278/
https://ncbi.nlm.nih.gov/pubmed/20637262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neulet.2010.07.013
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