MicroRNA-15b/16 enhances the induction of regulatory T cells by regulating the expression of Rictor and mTOR

Por Singh, Yogesh, Garden, Oliver A, Lang, Florian, Cobb, Bradley S
Publicado no J Immunol (2015)

MicroRNAs regulate T‐cell production of interleukin‐9 and identify hypoxia‐inducible factor‐2α as an important regulator of T helper 9 and regulatory T‐cell differentiation...

Por Singh, Yogesh, Garden, Oliver A., Lang, Florian, Cobb, Bradley S.
Publicado no Immunology (2016)

Retroviral Transduction of Helper T Cells as a Genetic Approach to Study Mechanisms Controlling their Differentiation and Function

Por Singh, Yogesh, Garden, Oliver A., Lang, Florian, Cobb, Bradley S.
Publicado no J Vis Exp (2016)

A common mechanism for mitotic inactivation of C2H2 zinc finger DNA-binding domains

Por Dovat, Sinisa, Ronni, Tapani, Russell, Dana, Ferrini, Roger, Cobb, Bradley S., Smale, Stephen T.
Publicado em 2002

A reappraisal of evidence for probabilistic models of allelic exclusion

Por Taylor, Benjamin, Cobb, Bradley S., Bruno, Ludovica, Webster, Zoe, Fisher, Amanda G., Merkenschlager, Matthias
Publicado em 2009

Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding

Por Cobb, Bradley S., Morales-Alcelay, Susana, Kleiger, Gary, Brown, Karen E., Fisher, Amanda G., Smale, Stephen T.
Publicado em 2000

MicroRNAs control the apoptotic threshold in primed pluripotent stem cells through regulation of BIM

Por Pernaute, Barbara, Spruce, Thomas, Smith, Kimberley M., Sánchez-Nieto, Juan Miguel, Manzanares, Miguel, Cobb, Bradley, Rodríguez, Tristan A.
Publicado em 2014

Cohesins form chromosomal cis-interactions at the developmentally regulated IFNG locus

Por Hadjur, Suzana, Williams, Luke M, Ryan, Natalie K., Cobb, Bradley S, Sexton, Tom, Fraser, Peter, Fisher, Amanda G, Merkenschlager, Matthias
Publicado em 2009

Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator

Por Trinh, Le A., Ferrini, Roger, Cobb, Bradley S., Weinmann, Amy S., Hahm, Kyungmin, Ernst, Patricia, Garraway, Isla P., Merkenschlager, Matthias, Smale, Stephen T.
Publicado em 2001

Dicer-dependent pathways regulate chondrocyte proliferation and differentiation

Por Kobayashi, Tatsuya, Lu, Jun, Cobb, Bradley S., Rodda, Stephen J., McMahon, Andrew P., Schipani, Ernestina, Merkenschlager, Matthias, Kronenberg, Henry M.
Publicado em 2008

The impact of chromatin modifiers on the timing of locus replication in mouse embryonic stem cells

Por Jørgensen, Helle F, Azuara, Véronique, Amoils, Shannon, Spivakov, Mikhail, Terry, Anna, Nesterova, Tatyana, Cobb, Bradley S, Ramsahoye, Bernard, Merkenschlager, Matthias, Fisher, Amanda G
Publicado em 2007

The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencing

Por Redrup, Lisa, Branco, Miguel R., Perdeaux, Elizabeth R., Krueger, Christel, Lewis, Annabelle, Santos, Fátima, Nagano, Takashi, Cobb, Bradley S., Fraser, Peter, Reik, Wolf
Publicado em 2009

Helios, a T cell-restricted Ikaros family member that quantitatively associates with Ikaros at centromeric heterochromatin

Por Hahm, Kyungmin, Cobb, Bradley S., McCarty, Aaron S., Brown, Karen E., Klug, Christopher A., Lee, Robert, Akashi, Koichi, Weissman, Irving L., Fisher, Amanda G., Smale, Stephen T.
Publicado em 1998

A role for Dicer in immune regulation

Por Cobb, Bradley S., Hertweck, Arnulf, Smith, James, O'Connor, Eric, Graf, Daniel, Cook, Terence, Smale, Stephen T., Sakaguchi, Shimon, Livesey, Frederick J., Fisher, Amanda G., Merkenschlager, Matthias
Publicado em 2006

T cell lineage choice and differentiation in the absence of the RNase III enzyme Dicer

Por Cobb, Bradley S., Nesterova, Tatyana B., Thompson, Elizabeth, Hertweck, Arnulf, O'Connor, Eric, Godwin, Jonathan, Wilson, Christopher B., Brockdorff, Neil, Fisher, Amanda G., Smale, Stephen T., Merkenschlager, Matthias
Publicado em 2005

Dicer regulates <it>Xist </it>promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a

Por Nesterova Tatyana B, Popova Bilyana C, Cobb Bradley S, Norton Sara, Senner Claire E, Tang Y Amy, Spruce Thomas, Rodriguez Tristan A, Sado Takashi, Merkenschlager Matthias, Brockdorff Neil
Publicado em 2008-10-01

Dicer regulates Xist promoter methylation in ES cells indirectly through transcriptional control of Dnmt3a

Por Nesterova, Tatyana B, Popova, Bilyana C, Cobb, Bradley S, Norton, Sara, Senner, Claire E, Tang, Y Amy, Spruce, Thomas, Rodriguez, Tristan A, Sado, Takashi, Merkenschlager, Matthias, Brockdorff, Neil
Publicado em 2008

MicroRNA miR-125a controls hematopoietic stem cell number

Por Guo, Shangqin, Lu, Jun, Schlanger, Rita, Zhang, Hao, Wang, Judy Y., Fox, Michelle C., Purton, Louise E., Fleming, Heather H., Cobb, Bradley, Merkenschlager, Matthias, Golub, Todd R., Scadden, David T.
Publicado em 2010

T cell receptor signaling controls Foxp3 expression via PI3K, Akt, and mTOR

Por Sauer, Stephan, Bruno, Ludovica, Hertweck, Arnulf, Finlay, David, Leleu, Marion, Spivakov, Mikhail, Knight, Zachary A., Cobb, Bradley S., Cantrell, Doreen, O'Connor, Eric, Shokat, Kevan M., Fisher, Amanda G., Merkenschlager, Matthias
Publicado em 2008

Runx proteins regulate Foxp3 expression

Por Bruno, Ludovica, Mazzarella, Luca, Hoogenkamp, Maarten, Hertweck, Arnulf, Cobb, Bradley S., Sauer, Stephan, Hadjur, Suzana, Leleu, Marion, Naoe, Yoshinori, Telfer, Janice C., Bonifer, Constanze, Taniuchi, Ichiro, Fisher, Amanda G., Merkenschlager, Matthias
Publicado em 2009