Targeting of Ikaros to pericentromeric heterochromatin by direct DNA binding

Ikaros is a sequence-specific DNA-binding protein that is essential for lymphocyte development. Little is known about the molecular function of Ikaros, although recent results have led to the hypothesis that it recruits genes destined for heritable inactivation to foci containing pericentromeric het...

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Autors principals: Cobb, Bradley S., Morales-Alcelay, Susana, Kleiger, Gary, Brown, Karen E., Fisher, Amanda G., Smale, Stephen T.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2000
Matèries:
Research Paper
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC316893/
https://ncbi.nlm.nih.gov/pubmed/10970879
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