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Binding of Ikaros to the λ5 promoter silences transcription through a mechanism that does not require heterochromatin formation
The Ikaros family of proteins are DNA binding factors required for correct development of B and T lymphocytes. Cytogenetic studies have shown that these proteins form complexes with pericentromeric heterochromatin in B cells, and the colocalization of transcriptionally silent genes with these comple...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2001
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC125479/ https://ncbi.nlm.nih.gov/pubmed/11387214 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2812 |
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