Binding of Ikaros to the λ5 promoter silences transcription through a mechanism that does not require heterochromatin formation
The Ikaros family of proteins are DNA binding factors required for correct development of B and T lymphocytes. Cytogenetic studies have shown that these proteins form complexes with pericentromeric heterochromatin in B cells, and the colocalization of transcriptionally silent genes with these comple...
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| Publicat a: | EMBO J |
|---|---|
| Autors principals: | , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Nature Publishing Group
2001
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11387214/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.11.2812 |
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