Binding of Ikaros to the λ5 promoter silences transcription through a mechanism that does not require heterochromatin formation

The Ikaros family of proteins are DNA binding factors required for correct development of B and T lymphocytes. Cytogenetic studies have shown that these proteins form complexes with pericentromeric heterochromatin in B cells, and the colocalization of transcriptionally silent genes with these comple...

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Veröffentlicht in:	EMBO J
Hauptverfasser:	Sabbattini, Pierangela, Lundgren, Mats, Georgiou, Andrew, Chow, Cheok-man, Warnes, Gary, Dillon, Niall
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Nature Publishing Group 2001
Schlagworte:	Article
Online-Zugang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC125479/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11387214/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/20.11.2812
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