Binding of Ikaros to the λ5 promoter silences transcription through a mechanism that does not require heterochromatin formation

The Ikaros family of proteins are DNA binding factors required for correct development of B and T lymphocytes. Cytogenetic studies have shown that these proteins form complexes with pericentromeric heterochromatin in B cells, and the colocalization of transcriptionally silent genes with these comple...

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Hlavní autoři: Sabbattini, Pierangela, Lundgren, Mats, Georgiou, Andrew, Chow, Cheok-man, Warnes, Gary, Dillon, Niall
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2001
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC125479/
https://ncbi.nlm.nih.gov/pubmed/11387214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/20.11.2812
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