Down-regulation of TDT transcription in CD4(+)CD8(+) thymocytes by Ikaros proteins in direct competition with an Ets activator

Ikaros is a unique regulator of lymphopoiesis that associates with pericentromeric heterochromatin and has been implicated in heritable gene inactivation. Binding and competition experiments demonstrate that Ikaros dimers compete with an Ets activator for occupancy of the lymphocyte-specific TdT pro...

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Dettagli Bibliografici

Pubblicato in:	Genes Dev
Autori principali:	Trinh, Le A., Ferrini, Roger, Cobb, Bradley S., Weinmann, Amy S., Hahm, Kyungmin, Ernst, Patricia, Garraway, Isla P., Merkenschlager, Matthias, Smale, Stephen T.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Cold Spring Harbor Laboratory Press 2001
Soggetti:	Research Paper
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC312741/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11459831/ https://ncbi.nlm.nih.govhttps://doi.org/10.1101/gad.905601
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