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MicroRNA miR-125a controls hematopoietic stem cell number

MicroRNAs influence hematopoietic differentiation, but little is known about their effects on the stem cell state. Here, we report that the microRNA processing enzyme Dicer is essential for stem cell persistence in vivo and a specific microRNA, miR-125a, controls the size of the stem cell population...

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Detalles Bibliográficos
Main Authors: Guo, Shangqin, Lu, Jun, Schlanger, Rita, Zhang, Hao, Wang, Judy Y., Fox, Michelle C., Purton, Louise E., Fleming, Heather H., Cobb, Bradley, Merkenschlager, Matthias, Golub, Todd R., Scadden, David T.
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2922532/
https://ncbi.nlm.nih.gov/pubmed/20616003
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0913574107
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