Regulation of synaptic structure and function by FMRP-associated microRNAs miR-125b and miR-132

MicroRNAs (miRNAs) are non-coding RNAs that suppress translation of specific mRNAs. The miRNA machinery interacts with Fragile X Mental Retardation Protein (FMRP), which functions as translational repressor. We show that miR-125b and miR-132, as well as several other miRNAs, are associated with FMRP...

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Vydáno v:Neuron
Hlavní autoři: Edbauer, Dieter, Neilson, Joel R., Foster, Kelly A., Wang, Chi-Fong, Seeburg, Daniel P., Batterton, Matthew N., Tada, Tomoko, Dolan, Bridget M., Sharp, Phillip A., Sheng, Morgan
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5018398/
https://ncbi.nlm.nih.gov/pubmed/20159450
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2010.01.005
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