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A reappraisal of evidence for probabilistic models of allelic exclusion

B cell development requires the coordinated rearrangement of Ig heavy (IgH) and light chain loci (IgL). Most mature B cells express a single B cell receptor of unique specificity, and a central question in immunology concerns the mechanisms that prevent the productive rearrangement of >1 IgH and...

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Detalhes bibliográficos
Main Authors: Taylor, Benjamin, Cobb, Bradley S., Bruno, Ludovica, Webster, Zoe, Fisher, Amanda G., Merkenschlager, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626735/
https://ncbi.nlm.nih.gov/pubmed/19116266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0808764105
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