Unified Synthesis of Polycyclic Alkaloids by Complementary Carbonyl Activation

por He, Guoli, List, Benjamin, Christmann, Mathias
Publicado en Angew Chem Int Ed Engl (2021)

Multivalent polyglycerol supported imidazolidin-4-one organocatalysts for enantioselective Friedel–Crafts alkylations

por Pecchioli, Tommaso, Muthyala, Manoj Kumar, Haag, Rainer, Christmann, Mathias
Publicado en Beilstein J Org Chem (2015)

In Situ Synthesis and Applications for Polyinterhalides Based on BrCl

por Schmidt, Benjamin, Ponath, Sebastian, Hannemann, Johannes, Voßnacker, Patrick, Sonnenberg, Karsten, Christmann, Mathias, Riedel, Sebastian
Publicado en Chemistry (2020)

Bioinspired synthesis of pentacyclic onocerane triterpenoids

por Bartels, Florian, Hong, Young J., Ueda, Daijiro, Weber, Manuela, Sato, Tsutomu, Tantillo, Dean J., Christmann, Mathias
Publicado en Chem Sci (2017)

Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis

por Driller, Ronja, Janke, Sophie, Fuchs, Monika, Warner, Evelyn, Mhashal, Anil R., Major, Dan Thomas, Christmann, Mathias, Brück, Thomas, Loll, Bernhard
Publicado en Nat Commun (2018)

Identification of an (−)‐englerin A analogue, which antagonizes (−)‐englerin A at TRPC1/4/5 channels

por Rubaiy, Hussein N, Seitz, Tobias, Hahn, Sven, Choidas, Axel, Habenberger, Peter, Klebl, Bert, Dinkel, Klaus, Nussbaumer, Peter, Waldmann, Herbert, Christmann, Mathias, Beech, David J
Publicado en Br J Pharmacol (2018)

Na(+) entry through heteromeric TRPC4/C1 channels mediates (−)Englerin A-induced cytotoxicity in synovial sarcoma cells

por Muraki, Katsuhiko, Ohnishi, Kaori, Takezawa, Akiho, Suzuki, Hiroka, Hatano, Noriyuki, Muraki, Yukiko, Hamzah, Nurasyikin, Foster, Richard, Waldmann, Herbert, Nussbaumer, Peter, Christmann, Mathias, Bon, Robin S., Beech, David J.
Publicado en Sci Rep (2017)

N‐Hydroxysuccinimide‐Modified Ethynylphosphonamidates Enable the Synthesis of Configurationally Defined Protein Conjugates

por Kasper, Marc‐André, Gerlach, Marcus, Schneider, Anselm F. L., Groneberg, Christiane, Ochtrop, Philipp, Boldt, Stefanie, Schumacher, Dominik, Helma, Jonas, Leonhardt, Heinrich, Christmann, Mathias, Hackenberger, Christian P. R.
Publicado en Chembiochem (2020)

(–)-Englerin A is a potent and selective activator of TRPC4 and TRPC5 calcium channels

por Akbulut, Yasemin, Gaunt, Hannah J, Muraki, Katsuhiko, Ludlow, Melanie J, Amer, Mohamed S, Bruns, Alexander, Vasudev, Naveen S, Radtke, Lea, Willot, Matthieu, Hahn, Sven, Seitz, Tobias, Ziegler, Slava, Christmann, Mathias, Beech, David J, Waldmann, Herbert
Publicado en Angew Chem Int Ed Engl (2015)

TRPC4/TRPC5 channels mediate adverse reaction to the cancer cell cytotoxic agent (-)-Englerin A

por Cheung, Sin Ying, Henrot, Matthias, Al-Saad, Mohammad, Baumann, Matthias, Muller, Heiko, Unger, Anke, Rubaiy, Hussein N., Mathar, Ilka, Dinkel, Klaus, Nussbaumer, Peter, Klebl, Bert, Freichel, Marc, Rode, Baptiste, Trainor, Sebastian, Clapcote, Steven J., Christmann, Mathias, Waldmann, Herbert, Abbas, Syed Khawar, Beech, David J., Vasudev, Naveen S.
Publicado en Oncotarget (2018)

Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels

por Rubaiy, Hussein N., Ludlow, Melanie J., Henrot, Matthias, Gaunt, Hannah J., Miteva, Katarina, Cheung, Sin Ying, Tanahashi, Yasuyuki, Hamzah, Nurasyikin, Musialowski, Katie E., Blythe, Nicola M., Appleby, Hollie L., Bailey, Marc A., McKeown, Lynn, Taylor, Roger, Foster, Richard, Waldmann, Herbert, Nussbaumer, Peter, Christmann, Mathias, Bon, Robin S., Muraki, Katsuhiko, Beech, David J.
Publicado en J Biol Chem (2017)