Picomolar, selective, and subtype-specific small-molecule inhibition of TRPC1/4/5 channels

The concentration of free cytosolic Ca(2+) and the voltage across the plasma membrane are major determinants of cell function. Ca(2+)-permeable non-selective cationic channels are known to regulate these parameters, but understanding of these channels remains inadequate. Here we focus on transient r...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:J Biol Chem
Main Authors: Rubaiy, Hussein N., Ludlow, Melanie J., Henrot, Matthias, Gaunt, Hannah J., Miteva, Katarina, Cheung, Sin Ying, Tanahashi, Yasuyuki, Hamzah, Nurasyikin, Musialowski, Katie E., Blythe, Nicola M., Appleby, Hollie L., Bailey, Marc A., McKeown, Lynn, Taylor, Roger, Foster, Richard, Waldmann, Herbert, Nussbaumer, Peter, Christmann, Mathias, Bon, Robin S., Muraki, Katsuhiko, Beech, David J.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2017
Fag:
Molecular Biophysics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5437225/
https://ncbi.nlm.nih.gov/pubmed/28325835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.773556
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker