Natural and synthetic flavonoid modulation of TRPC5 channels

BACKGROUND AND PURPOSE: The TRPC5 proteins assemble to create calcium‐permeable, non‐selective, cationic channels. We sought novel modulators of these channels through studies of natural products. EXPERIMENTAL APPROACH: Intracellular calcium measurements and patch clamp recordings were made from cel...

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Publicat a:Br J Pharmacol
Autors principals: Naylor, Jacqueline, Minard, Aisling, Gaunt, Hannah J, Amer, Mohamed S, Wilson, Lesley A, Migliore, Marco, Cheung, Sin Y, Rubaiy, Hussein N, Blythe, Nicola M, Musialowski, Katie E, Ludlow, Melanie J, Evans, William D, Green, Ben L, Yang, Hongjun, You, Yun, Li, Jing, Fishwick, Colin W G, Muraki, Katsuhiko, Beech, David J, Bon, Robin S
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2016
Matèries:
Research Papers
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728423/
https://ncbi.nlm.nih.gov/pubmed/26565375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13387
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