Natural and synthetic flavonoid modulation of TRPC5 channels

BACKGROUND AND PURPOSE: The TRPC5 proteins assemble to create calcium‐permeable, non‐selective, cationic channels. We sought novel modulators of these channels through studies of natural products. EXPERIMENTAL APPROACH: Intracellular calcium measurements and patch clamp recordings were made from cel...

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Detalles Bibliográficos
Publicado en:Br J Pharmacol
Main Authors: Naylor, Jacqueline, Minard, Aisling, Gaunt, Hannah J, Amer, Mohamed S, Wilson, Lesley A, Migliore, Marco, Cheung, Sin Y, Rubaiy, Hussein N, Blythe, Nicola M, Musialowski, Katie E, Ludlow, Melanie J, Evans, William D, Green, Ben L, Yang, Hongjun, You, Yun, Li, Jing, Fishwick, Colin W G, Muraki, Katsuhiko, Beech, David J, Bon, Robin S
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728423/
https://ncbi.nlm.nih.gov/pubmed/26565375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13387
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