Natural and synthetic flavonoid modulation of TRPC5 channels

BACKGROUND AND PURPOSE: The TRPC5 proteins assemble to create calcium‐permeable, non‐selective, cationic channels. We sought novel modulators of these channels through studies of natural products. EXPERIMENTAL APPROACH: Intracellular calcium measurements and patch clamp recordings were made from cel...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Naylor, Jacqueline, Minard, Aisling, Gaunt, Hannah J, Amer, Mohamed S, Wilson, Lesley A, Migliore, Marco, Cheung, Sin Y, Rubaiy, Hussein N, Blythe, Nicola M, Musialowski, Katie E, Ludlow, Melanie J, Evans, William D, Green, Ben L, Yang, Hongjun, You, Yun, Li, Jing, Fishwick, Colin W G, Muraki, Katsuhiko, Beech, David J, Bon, Robin S
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2016
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4728423/
https://ncbi.nlm.nih.gov/pubmed/26565375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13387
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