Hepatocyte nuclear factor 4α regulation of bile acid and drug metabolism

Por Chiang, John YL
Publicado em 2009

Recent advances in understanding bile acid homeostasis

Por Chiang, John YL
Publicado no F1000Res (2017)

Protein Kinase Cβ: Linking Intestine Fibroblast Growth Factor 15 to Hepatic Extracellular Signal Regulated Kinase 1/2 Signaling in Bile Acid and Cholesterol Homeostasis

Por Chiang, John Y.L.
Publicado no Cell Mol Gastroenterol Hepatol (2015)

Linking Sex Differences in Non-Alcoholic Fatty Liver Disease to Bile Acid Signaling, Gut Microbiota, and High Fat Diet

Por Chiang, John Y.L.
Publicado no Am J Pathol (2017)

Rifampicin Induction of CYP3A4 Requires PXR crosstalk with HNF4α and co-activators, and suppression of SHP gene Expression

Por Li, Tiangang, Chiang, John Y.L.
Publicado em 2006

Circadian rhythms in liver metabolism and disease

Por Ferrell, Jessica M., Chiang, John Y.L.
Publicado no Acta Pharm Sin B (2015)

Short-Term Circadian Disruption Impairs Bile Acid and Lipid Homeostasis in Mice

Por Ferrell, Jessica M., Chiang, John Y.L.
Publicado no Cell Mol Gastroenterol Hepatol (2015)

Bile acids and cytokines inhibit the human cholesterol 7α-hydroxylase gene via the JNK/c-Jun pathway

Por Li, Tiangang, Jahan, Asmeen, Chiang, John Y.L.
Publicado em 2006

A prospero-related homeodomain protein is a novel co-regulator of hepatocyte nuclear factor 4 α that regulates the cholesterol 7α-hydroxylase...

Por Song, Kwang-Hoon, Li, Tiangang, Chiang, John Y.L.
Publicado em 2006

G protein-coupled bile acid receptor plays a key role in bile acid metabolism and fasting-induced hepatic steatosis

Por Donepudi, Ajay C., Boehme, Shannon, Li, Feng, Chiang, John Y.L.
Publicado no Hepatology (2016)

Insulin regulation of cholesterol 7α-hydroxylase expression in human hepatocytes: Roles of forkhead box O1 and sterol regulatory element-binding protein 1c*

Por Li, Tiangang, Kong, Xiaoying, Owsley, Erika, Ellis, Ewa, Strom, Stephan, Chiang, John Y.L.
Publicado em 2006

Deficiency of cholesterol 7α‐hydroxylase in bile acid synthesis exacerbates alcohol‐induced liver injury in mice

Por Donepudi, Ajay C., Ferrell, Jessica M., Boehme, Shannon, Choi, Hueng‐Sik, Chiang, John Y.L.
Publicado no Hepatol Commun (2017)

Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice

Por Qi, Yunpeng, Jiang, Changtao, Cheng, Jie, Krausz, Kristopher W., Li, Tiangang, Ferrell, Jessica M., Gonzalez, Frank J., Chiang, John Y.L.
Publicado no Biochim Biophys Acta (2014)

Targeting the Enterohepatic Bile Acid Signaling Induces Hepatic Autophagy via a CYP7A1–AKT–mTOR Axis in Mice

Por Wang, Yifeng, Ding, Yifeng, Li, Jibiao, Chavan, Hemantkumar, Matye, David, Ni, Hong-Min, Chiang, John Y.L., Krishnamurthy, Partha, Ding, Wen-Xing, Li, Tiangang
Publicado no Cell Mol Gastroenterol Hepatol (2016)

All-trans-Retinoic Acid Ameliorates Hepatic Steatosis in Mice via a Novel Transcriptional Cascade

Por Kim, Seong Chul, Kim, Chunki, Axe, David, Cook, Aaron, Lee, Mikang, Li, Tiangang, Smallwood, Nicole, Chiang, John Y.L., Hardwick, James P., Moore, David D., Lee, Yoon Kwang
Publicado em 2014

Orphan nuclear receptor oestrogen-related receptor γ (ERRγ) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression

Por Zhang, Yaochen, Kim, Don-Kyu, Lee, Ji-Min, Park, Seung Bum, Jeong, Won-IL, Kim, Seong Heon, Lee, In-Kyu, Lee, Chul-Ho, Chiang, John Y.L., Choi, Hueng-Sik
Publicado no Biochem J (2015)

Fenofibrate differentially regulates PAI-1 gene expression via AMPK-dependent induction of orphan nuclear receptor SHP

Por Chanda, Dipanjan, Lee, Chul Ho, Kim, Yong-Hoon, Noh, Jung-Ran, Kim, Don-Kyu, Park, Ji-Hoon, Hwang, Jung Hwan, Lee, Mi-Ran, Jeong, Kyeong-Hoon, Lee, In-Kyu, Kweon, Gi Ryang, Shong, Minho, Oh, Goo-Taeg, Chiang, John Y.L., Choi, Hueng-Sik
Publicado em 2009