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Deficiency of cholesterol 7α‐hydroxylase in bile acid synthesis exacerbates alcohol‐induced liver injury in mice

Alcoholic fatty liver disease (AFLD) is a major risk factor for cirrhosis‐associated liver diseases. Studies demonstrate that alcohol increases serum bile acids in humans and rodents. AFLD has been linked to cholestasis, although the physiologic relevance of increased bile acids in AFLD and the unde...

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Dades bibliogràfiques
Publicat a:Hepatol Commun
Autors principals: Donepudi, Ajay C., Ferrell, Jessica M., Boehme, Shannon, Choi, Hueng‐Sik, Chiang, John Y.L.
Format: Artigo
Idioma:Inglês
Publicat: John Wiley and Sons Inc. 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776875/
https://ncbi.nlm.nih.gov/pubmed/29404516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1129
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