Deficiency of cholesterol 7α‐hydroxylase in bile acid synthesis exacerbates alcohol‐induced liver injury in mice

Alcoholic fatty liver disease (AFLD) is a major risk factor for cirrhosis‐associated liver diseases. Studies demonstrate that alcohol increases serum bile acids in humans and rodents. AFLD has been linked to cholestasis, although the physiologic relevance of increased bile acids in AFLD and the unde...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Hepatol Commun
Main Authors: Donepudi, Ajay C., Ferrell, Jessica M., Boehme, Shannon, Choi, Hueng‐Sik, Chiang, John Y.L.
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2017
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5776875/
https://ncbi.nlm.nih.gov/pubmed/29404516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep4.1129
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki