Bile acid signaling in lipid metabolism: Metabolomic and lipidomic analysis of lipid and bile acid markers linked to anti-obesity and anti-diabetes in mice

Bile acid synthesis is the major pathway for catabolism of cholesterol. Cholesterol 7α-hydroxylase (CYP7A1) is the rate-limiting enzyme in the bile acid biosynthetic pathway in the liver and plays an important role in regulating lipid, glucose and energy metabolism. Transgenic mice overexpressing CY...

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Bibliografiske detaljer
Udgivet i:Biochim Biophys Acta
Main Authors: Qi, Yunpeng, Jiang, Changtao, Cheng, Jie, Krausz, Kristopher W., Li, Tiangang, Ferrell, Jessica M., Gonzalez, Frank J., Chiang, John Y.L.
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4219936/
https://ncbi.nlm.nih.gov/pubmed/24796972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2014.04.008
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