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Orphan nuclear receptor oestrogen-related receptor γ (ERRγ) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression

Bile acids are primarily synthesized from cholesterol in the liver and have important roles in dietary lipid absorption and cholesterol homoeostasis. Detailed roles of the orphan nuclear receptors regulating cholesterol 7α-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis, have n...

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Dettagli Bibliografici
Pubblicato in:Biochem J
Autori principali: Zhang, Yaochen, Kim, Don-Kyu, Lee, Ji-Min, Park, Seung Bum, Jeong, Won-IL, Kim, Seong Heon, Lee, In-Kyu, Lee, Chul-Ho, Chiang, John Y.L., Choi, Hueng-Sik
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333639/
https://ncbi.nlm.nih.gov/pubmed/26348907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141494
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