Hypoxia Induces PDK4 Gene Expression through Induction of the Orphan Nuclear Receptor ERRγ

Multiple cellular signaling pathways that control metabolism and survival are activated when cell are incubated under hypoxic conditions. Activation of the hypoxia inducible factor (HIF)-1 promotes expression of genes that increase the capacity to cope with the stress imposed by a reduced oxygen env...

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Bibliographic Details
Main Authors: Lee, Ja Hee, Kim, Eun-Jin, Kim, Don-Kyu, Lee, Ji-Min, Park, Seung Bum, Lee, In-Kyu, Harris, Robert A., Lee, Mi-Ock, Choi, Hueng-Sik
Format: Artigo
Language:Inglês
Published: Public Library of Science 2012
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457976/
https://ncbi.nlm.nih.gov/pubmed/23050013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046324
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