Hypoxia Induces PDK4 Gene Expression through Induction of the Orphan Nuclear Receptor ERRγ

Multiple cellular signaling pathways that control metabolism and survival are activated when cell are incubated under hypoxic conditions. Activation of the hypoxia inducible factor (HIF)-1 promotes expression of genes that increase the capacity to cope with the stress imposed by a reduced oxygen env...

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Main Authors: Lee, Ja Hee, Kim, Eun-Jin, Kim, Don-Kyu, Lee, Ji-Min, Park, Seung Bum, Lee, In-Kyu, Harris, Robert A., Lee, Mi-Ock, Choi, Hueng-Sik
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3457976/
https://ncbi.nlm.nih.gov/pubmed/23050013
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0046324
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