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Orphan nuclear receptor oestrogen-related receptor γ (ERRγ) plays a key role in hepatic cannabinoid receptor type 1-mediated induction of CYP7A1 gene expression

Bile acids are primarily synthesized from cholesterol in the liver and have important roles in dietary lipid absorption and cholesterol homoeostasis. Detailed roles of the orphan nuclear receptors regulating cholesterol 7α-hydroxylase (CYP7A1), the rate-limiting enzyme in bile acid synthesis, have n...

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Detalhes bibliográficos
Publicado no:Biochem J
Main Authors: Zhang, Yaochen, Kim, Don-Kyu, Lee, Ji-Min, Park, Seung Bum, Jeong, Won-IL, Kim, Seong Heon, Lee, In-Kyu, Lee, Chul-Ho, Chiang, John Y.L., Choi, Hueng-Sik
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5333639/
https://ncbi.nlm.nih.gov/pubmed/26348907
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141494
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