Genetic control of murine invariant natural killer T-cell development dynamically differs dependent on the examined tissue type

Por Chen, Yi-Guang, Tsaih, Shirng-Wern, Serreze, David V.
Publicado em 2011

Comparative Genetics: Synergizing Human and NOD Mouse Studies for Identifying Genetic Causation of Type 1 Diabetes

Por Driver, John P., Chen, Yi-Guang, Mathews, Clayton E.
Publicado em 2012

The Role of NOD Mice in Type 1 Diabetes Research: Lessons from the Past and Recommendations for the Future

Por Chen, Yi-Guang, Mathews, Clayton E., Driver, John P.
Publicado no Front Endocrinol (Lausanne) (2018)

Combined congenic mapping and nuclease-based gene targeting for studying allele-specific effects of Tnfrsf9 within the Idd9.3 autoimmune diabetes locus

Por Forsberg, Matthew H., Foda, Bardees, Serreze, David V., Chen, Yi-Guang
Publicado no Sci Rep (2019)

Repeated Activation of Lung Invariant NKT Cells Results in Chronic Obstructive Pulmonary Disease-Like Symptoms

Por Tsao, Cheng-Chiu, Tsao, Po-Nien, Chen, Yi-Guang, Chuang, Ya-Hui
Publicado no PLoS One (2016)

Blood-based signatures in type 1 diabetes

Por Cabrera, Susanne M., Chen, Yi-Guang, Hagopian, William A., Hessner, Martin J.
Publicado no Diabetologia (2015)

Unmasking Genes in a Type 1 Diabetes–Resistant Mouse Strain That Enhances Pathogenic CD8 T-Cell Responses

Por Driver, John P., Chen, Yi-Guang, Zhang, Weidong, Asrat, Seblewongel, Serreze, David V.
Publicado em 2011

Genetic control of murine invariant natural killer T-cells maps to multiple type 1 diabetes regions

Por Tsaih, Shirng-Wern, Khaja, Shamim, Ciecko, Ashley E., MacKinney, Erin, Chen, Yi-Guang
Publicado em 2013

Homeostasis of IL-15 dependent lymphocyte subsets in the liver

Por Cepero-Donates, Yuneivy, Rakotoarivelo, Volatiana, Mayhue, Marian, Ma, Averil, Chen, Yi-Guang, Ramanathan, Sheela
Publicado no Cytokine (2016)

Congenic mapping identifies a novel Idd9 subregion regulating type 1 diabetes in NOD mice

Por Lin, Bixuan, Ciecko, Ashley E., MacKinney, Erin, Serreze, David V., Chen, Yi-Guang
Publicado no Immunogenetics (2016)

Invariant Natural Killer T-Cell Control of Type 1 Diabetes: A Dendritic Cell Genetic Decision of a Silver Bullet or Russian Roulette

Por Driver, John P., Scheuplein, Felix, Chen, Yi-Guang, Grier, Alexandra E., Wilson, S. Brian, Serreze, David V.
Publicado em 2010

A recombinant heavy chain antibody approach blocks ART2 mediated deletion of an iNKT cell population that upon activation inhibits autoimmune diabetes

Por Scheuplein, Felix, Rissiek, Björn, Driver, John P., Chen, Yi-Guang, Koch-Nolte, Friedrich, Serreze, David V.
Publicado em 2009

A locus on mouse Chromosome 13 inversely regulates CD1d expression and the development of invariant natural killer T-cells

Por Tsaih, Shirng-Wern, Presa, Maximiliano, Khaja, Shamim, Ciecko, Ashley E., Serreze, David V., Chen, Yi-Guang
Publicado no Genes Immun (2015)

UBASH3A deficiency accelerates type 1 diabetes development and enhances salivary gland inflammation in NOD mice

Por Chen, Yi-Guang, Ciecko, Ashley E., Khaja, Shamim, Grzybowski, Michael, Geurts, Aron M., Lieberman, Scott M.
Publicado no Sci Rep (2020)

Idd9/11 Genetic Locus Regulates Diabetogenic Activity of CD4 T-Cells in Nonobese Diabetic (NOD) Mice

Por Chen, Yi-Guang, Scheuplein, Felix, Osborne, Melissa A., Tsaih, Shirng-Wern, Chapman, Harold D., Serreze, David V.
Publicado em 2008

Gene Targeting in NOD Mouse Embryos Using Zinc-Finger Nucleases

Por Chen, Yi-Guang, Forsberg, Matthew H., Khaja, Shamim, Ciecko, Ashley E., Hessner, Martin J., Geurts, Aron M.
Publicado em 2014

CD137 ligand is important for type 1 diabetes development but dispensable for the homeostasis of disease suppressive CD137(+) FOXP3(+) regulatory CD4 T cells

Por Foda, Bardees M., Ciecko, Ashley E., Serreze, David V., Ridgway, William M., Geurts, Aron M., Chen, Yi-Guang
Publicado no J Immunol (2020)

CD137 plays both pathogenic and protective roles in type 1 diabetes development in NOD mice

Por Forsberg, Matthew H., Ciecko, Ashley E., Bednar, Kyle J., Itoh, Arata, Kachapati, Kritika, Ridgway, William M., Chen, Yi-Guang
Publicado no J Immunol (2017)

Testing the role of P2X(7) receptors in the development of type 1 diabetes in NOD mice

Por Chen, Yi-Guang, Scheuplein, Felix, Driver, John P., Hewes, Amanda A., Reifsnyder, Peter C., Leiter, Edward H., Serreze, David V.
Publicado em 2011

Interleukin-1 antagonism moderates the inflammatory state associated with Type 1 diabetes during clinical trials conducted at disease onset

Por Cabrera, Susanne M., Wang, Xujing, Chen, Yi-Guang, Jia, Shuang, Kaldunski, Mary L., Greenbaum, Carla J., Mandrup-Poulsen, Thomas, Hessner, Martin J.
Publicado no Eur J Immunol (2016)